FX1 is a Specific BCL6 Inhibitor for Lymphoma Research
Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. Mutations in BCL6 can lead to B cell lymphomas because it promotes unchecked B…
Bcl-6 (B-cell lymphoma 6) is a protein that in humans is encoded by the BCL6 gene. Mutations in BCL6 can lead to B cell lymphomas because it promotes unchecked B…
As we know, Bruton tyrosine kinase (Btk) is a member of the TEC family kinases. In addition, it is involved in B-cell antigen receptor (BCR)-signaling pathway. Usually, BTK is expressed…
Autophagy is the natural and conservative degradation of cells. Specifically, it can remove unnecessary or dysfunctional components through lysosomal-dependent regulation mechanisms. Besides, it allows the orderly degradation and recycling of…
Protein degradation agents based on the ubiquitin-proteasome pathway include a part of molecular glues. A molecular glue is a small molecule that stabilizes the interaction between two proteins that do…
Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and a catalytic component of polycomb repressive complex 2 (PRC2). EZH2 catalyzes tri-methylation of histone H3 at Lys 27 (H3K27me3)…