ARV-825 is a PROTAC Degrader of BRD4 with Profound Anti-Leukemic Effect
BRD4 (Bromodomain-containing protein 4) belongs to the BET family, which also contains BRD2, BRD3, and BRDT. BRD4 has two bromodomains to recognize acetylated lysine residues. They are BD1 and BD2.…