Nilotinib is an Orally Active Bcr-Abl Tyrosine Kinase Inhibitor for CML Research
BCR-ABL tyrosine kinase, an abnormal fusion protein kinase, is associated with pathogenesis of chronic myelogenous leukemia (CML) and Ph+ acute lymphoblastic leukemia (ALL). Usually, BCR-ABL is overexpressed with CML stem…