Plerixafor is a Selective CXCR4 Antagonist and Mobilizes Hematopoietic Stem Cells in Cancer
CXCR4 is a chemokine receptor mainly located on the cell membrane of CD34+ cells and various inflammatory cells. SDF-1α/CXCL12 (chemokine stromal cell-derived factor 1 α) is a ligand of CXCR4. It…