Zotatifin is a Selective and Well-Tolerated eIF4A (Protein Biogenesis) Inhibitor
In this article, we will introduce a potent, selective, and well-tolerated eIF4A inhibitor, Zotatifin. It promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM). Zotatifin…