SIM1 is a PROTAC Based BET Family Degrader
Proteolytic targeting chimera (PROTAC) is a heterobifunctional small molecule that acts by inducing selective intracellular...
Proteolytic targeting chimera (PROTAC) is a heterobifunctional small molecule that acts by inducing selective intracellular...
Protein-protein interactions (PPIs) play a key role in nearly every biological function. And PPIs are...
The proteins of BET (bromodomain and extra-terminal) domain family are epigenetic readers. BET domain family...
The bromodomain and extra-terminal (BET) family of proteins are epigenetic readers of chromatin. The two...
A Bromodomain (BRD) is a protein domain of about 110 amino acids and is a...
Brominedomain can recognize acetylated lysine residues. As the “reader” of lysine acetylation, the bromine domain...
Come straight to the point, CC-90010 (compound 1) is a reversible and orally active BET...
BRD4 is a member of the BET family of proteins (BRD2, 3, 4, and T)....
The bromodomain and extra-terminal (BET) family proteins consist of BRD2, BRD3, BRD4, and testis-specific BRDT...
NUT midline carcinoma (NMC) is a rare, aggressive subtype of squamous carcinoma. This kind of...