LC-MB12 is a FGFR2 PROTAC Degrader for Gastric Cancer Research
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is...
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is...
PROTACs are bi-functional molecules, capable of concurrently binding to target proteins of interest and the...
Proteolysis targeting chimeras (PROTAC) is a bifunctional molecule that could draw an E3 ubiquitin ligase...
BRD9 is a subunit of the human BAF (SWI/SNF) nucleosome remodeling complex. Besides, BRD9 contains...
Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of polycomb repressive complex 2...
Histone deacetylase 8 (HDAC8) is a class I histone deacetylase. Unlike other class I HDACs,...
Ph+ ALL (Philadelphia chromosome-positive acute lymphoblastic leukemia) is a rare subtype of leukemia characterized by...
Chronic myeloid leukemia (CML) is a kind of myeloproliferative neoplasms (MPN). It is characterized by...
CRLF2-rearranged (CRLF2r) acute lymphoblastic leukemia (ALL) is relevant with a poor outcome in children and...
SWI/SNF complex has two important ATP-dependent helicases, SMARCA2 and SMARCA4. In fact, SMARCA2 and SMARCA4...