Relugolix is an Orally Active GnRH Antagonist for Prostate Cancer and Uterine Fibroids Research
In humans, the hypothalamic-pituitary-gonadal (HPG) axis is critical for reproduction and the expression of sexual...
In humans, the hypothalamic-pituitary-gonadal (HPG) axis is critical for reproduction and the expression of sexual...
CYP17A1 is a bifunctional hydroxylase that belongs to the cytochrome P450 family. It has 17α-hydroxylase...
Among numerous cancers, prostate cancer is one of the most common cancers in men. Androgens...
mTOR, the mammalian target of rapamycin, is a conserved serine/threonine kinase. mTOR often serves as...
Ovarian cancer (OC) is the eighth most common neoplasia in women, and the fifth leading...
Androgen receptor (AR), is a member of the nuclear hormone receptor superfamily. AR is involved in...
Proteolysis targeting chimeras (PROTAC) is a bifunctional molecule that could draw an E3 ubiquitin ligase...
Ras proteins play a crucial role in tumor diseases. Farnesylation is an important post-translational modification...
GnRHR (gonadotropin-releasing hormone receptor) is also known as the luteinizing hormone-releasing hormone receptor (LHRHR). Importantly,...
The androgen receptor (AR) is a nuclear receptor, which can mediate the cellular action of...