B7-H3 (CD276) is a T cell co-stimulator and co-suppressor molecule. Specifically, B7-H3 plays an important role in tumor cell apoptosis, proliferation, adhesion, angiogenesis, invasion, migration, and escape from immune surveillance. Effects of B7-H3 on T cell proliferation, activation, and IFN in vitro-γ show a positive regulatory function during production....