Tag: drug-resistant

NecroIr2 is an Iridium(III) Complex, Can be Used as an Anticancer Agent

Inorganic elements play crucial roles in biomedical processes. Many inorganic elements such as transition metals have anticancer activities. Even though metal complexes are making progress against cancer, cisplatin (CDDP) remains the most widely used first-line chemotherapeutic drug for various cancers. Drug resistance to cisplatin significantly limits its clinical use...

LTX-315 is an Oncolytic Peptide with Potent Anticancer Activity

Oncolytic peptides offer yet a new therapeutic modality. Their membranolytic mode of action includes the release of danger-associated molecular pattern molecules (DAMPs) and tumor antigens from cancer cells. Therefore, it results in regression of solid tumors and systemic tumor-specific immune responses. Consequently, the development of oncolytic peptides into novel...