BI99179 is a Selective Type I FASN Inhibitor
Fatty acid synthase (FASN) is a key enzyme involved in neoplastic lipogenesis. In particular, the Overexpression of FASN is common in many cancers. FASN is a metabolic oncogene with an…
IPI-9119 is an Orally Active, Selective and Irreversible FASN Inhibitor
Fatty acid synthase (FASN) is a multi-enzyme protein that catalyzes the synthesis of fatty acids. Its main function is to catalyze the synthesis of palmitate (C16:0) from acetyl CoA and…
TVB-3166 is an Orally Active and Selective FASN Inhibitor
Fatty acid synthases (FASN) are homodimers and multifunctional enzymes that catalyze palmitate biosynthesis in NADPH dependent reactions. FASN plays an important role in tumor cell biology and therapeutic response of various…
FT113 is an Orally Active Inhibitor of Fatty Acid Synthase (FASN)
Fatty acid synthase (FAS) is a protein responsible for fatty acid synthesis. It mainly catalyzes palmitate synthesis from acetyl-CoA and malonyl-CoA, in the presence of NADPH. FAS gene is reported…