AAPK-25 is a Selective and Dual Aurora/PLK Inhibitor
The occurrence of many cancers is due to a mismatch of chromosomes. It leads to the formation of aneuploidy and incomplete genes, and hence triggering an imbalance of cell cycles or divisions in the mitotic phase. Aurora and Polo-like kinases (PLKs) control the G2/M phase in cell mitosis. They are...