NAZ2329 is an Allosteric Inhibitor of R5 RPTP Subfamily and PTPRZ/PTPRG
The R5 subfamily of receptor protein tyrosine phosphatases (RPTPs) includes PTPRZ and PTPRG. Specifically, PTPRZ1 is a member of the receptor tyrosine phosphatase family. Besides, PTPRZ1 encodes a one-way type I membrane protein with two cytoplasmic tyrosine-protein phosphatase domains, α-carbonic anhydrase domain, and fibronectin III domain. There is a...