RKI-1313 is a Potent ROCK1/2 inhibitor
ROCK is a kinase belonging to the AGC (PKA/PKG/PKC) family of serine threonine-specific protein kinases. Specifically, ROCK is one of the best characterization effectors of RhoA, a small GTPase. It…
ROCK is a kinase belonging to the AGC (PKA/PKG/PKC) family of serine threonine-specific protein kinases. Specifically, ROCK is one of the best characterization effectors of RhoA, a small GTPase. It…
Rho-associated protein kinases (ROCKs) are serine-threonine kinases contain isoforms ROCK1 and ROCK2. ROCK1 and ROCK2 exhibit 60% sequence homology and 90% kinase domain homology. The 2 isoforms exist in many…