Shp1 - Network of Cancer Research

BPDA2 is a Highly Selective and Competitive SHP2 Inhibitor

Louis Gilman February 22, 2023

SH2-containing protein tyrosine phosphatase 2 (SHP2) is a carcinogenic phosphatase. Specifically, SHP2 participates in the downstream signal transmission of various RTK. So it is the shared signal node for analysis.…

Breast Cancer

PHPS1 is a Selective Shp2 Inhibitor

Louis Gilman August 14, 2021

SHP2 is a non-receptor protein tyrosine phosphatase (PTP) encoded by the human PTPN11 gene. Particularly, SHP2 contains a PTP catalytic domain and two SH2 domains. SHP2 is a ubiquitous PTP…

BPDA2 is a Highly Selective and Competitive SHP2 Inhibitor

PHPS1 is a Selective Shp2 Inhibitor

You Missed

Erlotinib is an EGFR TKI for NSCLC and Pancreatic Cancer Research

Parsaclisib is an Orally Active PI3Kδ Inhibitor for B-cell Malignancies Research

Nilotinib is an Orally Active Bcr-Abl Tyrosine Kinase Inhibitor for CML Research

Temsirolimus is an mTOR Inhibitor for Kinds of Cancers Research