Sirtuins are NAD-dependent deacetylases that are involved in physiologic processes. To date, seven mammalian sirtuins have been identified (SIRT1–SIRT7). Sirtuin 1 (SIRT1) is a member of the sirtuin family of proteins. On the one hand, SIRT1 inhibition leads to growth arrest and apoptosis in lymphoma, breast, lung, and epithelial...