DVD-445 is a TrxR1 Inhibitor for Cancer Therapy
During multistep development, cancer cells acquire different biological capabilities such as sustaining proliferative signaling, activating invasion and metastasis. Activation of oncogenes, atypical changes in metabolism, and loss of p53 function during cancer progression may lead to oxidative stress. Oxidative stress results from the imbalance between the antioxidant capacity of...