Cevipabulin (TTI-237) is a Microtubule-Active Antitumor Compound
Microtubules are part of the mitotic spindle, the complex and dynamic structure that mediates chromosome separation during mitosis. Therefore, microtubules are a proven target in cancer treatment. There have been many clinical drugs designed to target microtubule, including Paclitaxel and Vinblastine. Vincristine binds at one of three known pharmacologic...