Acute leukemia is a kind of serious diseases, includes acute myeloid leukemia, acute lymphoblastic leukemia and blast crisis of chronic myelogenous leukemia. MLL1 (Mixed-lineage leukemia 1; KMT2A) is a histone methyltransferase, occurs in leukemia cells in a mutation form. MLL1 interacts with WD repeat domain 5 protein (WDR5), enhances...