SB 258719 is a Selective 5-HT7 Receptor Antagonist
The neurotransmitter 5-hydroxytryptamine (5-HT) has an array of pharmacological and physiological roles within the central nervous system. It has the potential to develop a number of useful medicines. The selective 5-hydroxytryptamine (5-HT, serotonin) reuptake inhibitors (SSRIs) show potency in major depression. 5-HT receptors divide into seven major classes (5-HT1-7)....
PU02 is an Allosteric Antagonist of 5-HT3 Receptor
Cancer is a usual disease and a leading cause of death in the world. Therefore, developing new agents specifically targeting cancer cells has achieved more and more researches. As it is widely believed that cancer can be treated by inducing tumor cells to undergo senescence or apoptosis, screening for...