EGFR stands for epidermal growth factor receptor, a tyrosine kinase and transmembrane receptor protein. It primarily functions to regulate epithelial tissue development and homeostasis. Moreover, EGFR is a driver of…
Heat shock protein (Hsp) 90 is a chaperone protein. In addition to protecting cells by correcting misfolded proteins, Hsp90 also plays a key role in regulating the stability, maturation, and…
Src homology 2 domain-containing phosphatase (SHP2) is a phosphatase that mediates signaling downstream of multiple receptor tyrosine kinases. SHP2 suppresses signaling through the MAPK pathway. Furthermore, SHP2 inhibition has demonstrated…