NVS-CECR2-1 is a CECR2 BRD (non-BET Family) Inhibitor
A Bromodomain (BRD) is a protein domain of about 110 amino acids and is a "reader" of lysine acetylation. Specifically, BRDs recognize acetylated lysine residues, such as those on the…
NU6102 is a Potent CDK1 and CDK2 Inhibitor
CDKs remain attractive targets for anti-proliferative cancer chemotherapy. they play a central role in cell division and growth. Amongst the cell cycle CDKs, CDK2 has attracted the most attention and…
IZCZ-3 is an Anticancer Agent by Blocking c-MYC Transcription
G-quadruplexes are unique four-stranded structures formed by guanine-rich nucleic acid sequences. G-quadruplexes are widely distributed in many important regulatory regions in the human genome, notably in telomeres and promoters of…