Flurbiprofen is a Non-selective COX Inhibitor for Colorectal Cancer Research
Flurbiprofen, COX, Colorectal Cancer, NSAIA, NSAID, antipyretic, analgesic, osteoarthritis, rheumatoid arthritis
Flurbiprofen, COX, Colorectal Cancer, NSAIA, NSAID, antipyretic, analgesic, osteoarthritis, rheumatoid arthritis
ATG4B is a cysteine protease that activates LC3 for lipidation and recent studies suggest that it may be another promising target to inhibit autophagy upstream of the lysosome. Consistent with…
FGFR (Fibroblast growth factor receptors), a family of receptor tyrosine kinases, are the receptors that bind to members of the fibroblast growth factor family of proteins. FGFRs play crucial roles…
FGFR (Fibroblast growth factor receptors) are the receptors that bind to members of the fibroblast growth factor family of proteins. The fibroblast growth factor family constitutes one of the most…
SYK is a non-receptor tyrosine kinase. Specifically, Syk is a key element in the B cell receptor signaling pathway. Besides, Syk is also a key component of signal transduction in…
Adenosine receptors (ARs) comprise a group of G protein-coupled receptors (GPCR) which mediate the physiological actions of adenosine. To date, there are four known types of adenosine receptors in humans:…
VEGF receptor (VEGFR) is the receptor for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR VEGFR 1/2/3. By alternative splicing modification, membrane-bound (mbVEGFR) or soluble (sVEGFR)…
ATM (ataxia-telangiectasia mutated) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. Importantly, In response to DSB, the ATM kinase undergoes autophosphorylation and subsequently phosphorylates…
Colon cancer is a common occurrence in a malignant tumor of the digestive tract with the high mortality rate, but low survival rate. However, colorectal cancer is the fourth most…
EGFR (epidermal growth factor receptor) is a member of the ErbB receptor family1. Besides, EGFR is a common therapeutic strategy in epithelioma such as lung adenocarcinoma, colon cancer, head and…