Large B Cell Lymphoma

Polatuzumab vedotin is a CD79b ADC for Large B-cell lymphomas (LBCL) Research

Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b for Large B-cell lymphomas (LBCL) Research. CD79b is a surface antigen whose expression is restricted to pre‐B and mature B cells. Besides,…

Large B Cell Lymphoma Lymphoma

CA-4948 is a Selective and Orally Bioavailable IRAK4 Kinase Inhibitor for Lymphoma Treatment

Louis Gilman January 5, 2020

Interleukin-1 receptor-associated kinase 4 (IRAK4) is the most upstream kinase in Toll/Interleukin-1 receptor (TIR) signaling. Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling in a variety of myeloid and lymphoid…