CH-223191 is a Specific Antagonist of Aryl Hydrocarbon Receptor (AhR) with Anti-Tumor Activity
In previous blog, we described CH-223191 as an antagonist of aryl hydrocarbon receptor (AhR). CH-223191 reduces the aggravation of arthritis induced by smoking in mice via aryl hydrocarbon receptor. Today, I’d like to say something about the anti-tumor activity of this antagonist. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant...