CGP52411 is an Orally Active and ATP-Competitive EGFR Inhibitor
The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein that mediates the response of cells to EGF and transforming growth factor α. Deregulated signal transduction via the EGFR family of protein-tyrosine kinase growth factor receptors is relevant to proliferative diseases. Besides, the EGFR is involved in epithelial proliferation...