Ferristatin (NSC306711) is a Potent Iron Transport Inhibitor and Promotes Transferrin Receptor Degradation
Iron is an essential nutrient required for DNA synthesis, energy production, and normal cellular growth. Meanwhile, Iron circulates in the plasma bound to transferrin (Tf). Particularly, Most cells express Tf receptors on their surface to bind and internalize Tf by receptor-mediated endocytosis. Importantly, Study shows that alterations in the...