Anti-Proliferation - Network of Cancer Research

BNS-22 is a DNA Topoisomerase II Catalytic Inhibitor

Louis Gilman August 18, 2022

Topoisomerases (DNA topoisomerases) are enzymes that catalyze changes in the topological state of DNA, regulating the overwinding or underwinding of DNA. Topoisomerases play essential roles in DNA replication, transcription, chromosome…

Cancer Liver Cancer

Vatalanib (PTK787) is an Inhibitor of VEGFR2/KDR

Louis Gilman June 12, 2022

Vascular endothelial growth factor receptor (VEGFR) is the receptor for VEGF. VEGF is an important signaling protein involved in both vasculogenesis and angiogenesis. VEGFRs consist of three subtypes, the fms-like…

Breast Cancer

BNS-22 is a DNA Topoisomerase II Catalytic Inhibitor

Vatalanib (PTK787) is an Inhibitor of VEGFR2/KDR

You Missed

BI 7446 is a STING Agonist for Immuno-oncology Research

JNJ-38877605 is an Orally Active c-Met Inhibitor for Solid Tumour Research

OATD-02 is an Orally Active Arginase 1/2 Inhibitor for Melanoma Research

INCB086550 is an Orally Active PD-L1 Inhibitor for Multiple Cancers Research