DS21360717 is an Orally Active FER Tyrosine Kinase Inhibitor
FER (Proto-oncogene tyrosine-protein kinase) is a kind of non-transmembrane receptor tyrosine kinases. It regulates cell-cell adhesion, involves in signaling from cell surface to the cytoskeleton through growth factor receptors. In breast cancers, FER expression exhibits high levels. This expression does not depend on prognostic factors. FER protein regulates cell...