iFSP1 is a Selective FSP1 Inhibitor Glutathione-Independently
Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to phospholipids. Selenoenzyme GPX4 could control Ferroptosis. Flavoprotein apoptosis-inducing factor mitochondria-associated 2 (AIFM2) is an anti-ferroptosis gene. AIFM2 (ferroptosis suppressor protein 1, FSP1) confers protection against ferroptosis elicited by GPX4 deletion. The anti-ferroptosis function of FSP1...