Activating mutations in NRAS account for 20%-30% of melanoma. but, there are no effective anti-NRAS therapies. Originally, it reports that the serine/threonine-protein kinase 19 (STK19) phosphorylate a-casein at serine/threonine residues and histones at serine residues. However, the role of STK19 in cancer initiation and development is poorly appreciated. Importantly,...