In this article, we introduce a specific inhibitor of transforming growth factor-β (TGF-β) -- PBrP. It suppresses TGF-β-induced cellular responsiveness by displacing type II TGF-β receptor (TβRII) from the plasma…
Rebeccamycin, a yellow crystalline product, is isolated from the mycelium. It has activity against P388 leukemia, L1210 leukemia, and B16 melanoma implanted in mice. Rebeccamycin is also an antitumor antibiotic…
Pirarubicin has widely application in intravesical chemotherapy for bladder cancer, but drug resistance limits its efficacy; the mechanism still needs further exploration. Bladder cancer is the most common malignancy…
Protein synthesis is a core biological process, which balances the loss of cellular proteins by producing new proteins. Specifically, proteins perform many key functions as enzymes, structural proteins, or hormones.…