ARQ 531 (MK-1026) is a Reversible Non-Covalent and Orally Active BTK Inhibitor
Bruton's tyrosine kinase (abbreviated Btk or BTK) is a tyrosine kinase that is encoded by the BTK gene in humans. BTK, a kinase expressed in B cells and bone marrow…
SB-332235 is an Orally Active CXCR2 Antagonist
Chemokines are low m.w. proteins that modulate the immune response through the chemoattraction and activation of leukocytes. These mediators have four classes. Chemokines in which the first two cysteines are…