Farnesyltransferase (FTase) is a zinc enzyme that has been the subject of particular attention in anti-cancer research. Inhibitors of farnesyltransferase (FTase) have been designed for use as anti-Ras and anti-cancer drugs, but in fact they are selective for FTase, not for Ras. The non-thiol-containing FTI-2148 is highly selective for...