MS8815 is a EZH2 PROTAC Degrader for Targeting Triple-Negative Breast Cancer (TNBC)
Enhancer of zeste homolog 2 (EZH2) is a catalytic subunit of polycomb repressive complex 2 (PRC2). EZH2 drives oncogenesis not only in a canonical H3K27me3-dependent manner but also through non-canonical…