VU0359595 is a Selective PLD1 Inhibitor
Phospholipase is a member of a very complex group of enzymes that break down phospholipids into fatty acids and other compounds. Phospholipase D (PLD) is an enzyme of the phospholipase superfamily. There are two mammalian isoforms of PLD, coined PLD1 and PLD2, and despite conserved regulatory and catalytic domains....
VU0155069, a Selective PLD1 Inhibitor, Blocks Tumor Cell Invasion
Phospholipase D (PLD) belongs to the phospholipase superfamily, which widely exists in animals, plants, yeast, bacteria, and viruses. In mammalian cells, there are two PLD isoforms, PLD1 and PLD2. The enzyme involves in various physiological processes, such as membrane trafficking, cytoskeletal reorganization, and cell migration. PLD is also related...