PHPS1 is a Selective Shp2 Inhibitor
SHP2 is a non-receptor protein tyrosine phosphatase (PTP) encoded by the human PTPN11 gene. Particularly, SHP2 contains a PTP catalytic domain and two SH2 domains. SHP2 is a ubiquitous PTP with a relatively conserved structure and function. Specifically, SHP2 is relevant to cell proliferation and differentiation induced by various...