Fasentin, a Chemical Sensitizer, Inhibits GLUT-1 and GLUT-4 Transporters
Angiogenesis forms new blood vessels from pre-existing ones. Angiogenesis is a physiological and transient process that in adults is limited to some processes. They include reproductive cycles, wound healing, and bone repair. Nevertheless, a persistent and deregulated angiogenesis takes place in cancer and other diseases, such as proliferative retinopathies,...
GSK3145095 is a RIP1 Kinase Inhibitor for the Treatment of Pancreatic Cancer
Receptor interacting protein (RIP) kinases are a group of threonine/serine protein kinases. They have a relatively conserved kinase domain but distinct non-kinase regions. The RIP kinases contain seven members, all of which share a homologous kinase domain but have different functional domains. RIP1 contains a C-terminal death domain, through...