ML-097 (CID-2160985) is a Pan Ras-related GTPases Activator
Ras, is a family of related proteins expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase. Furthermore,…
Ras, is a family of related proteins expressed in all animal cell lineages and organs. All Ras protein family members belong to a class of protein called small GTPase. Furthermore,…
To date, we identified 167 small GTPases in humans which are key signal transducing enzymes. Small GTPases comprise five main families whose eponymous members are Ras, Rho, Rab, ADP-ribosylation factor…
Alteration of small GTPase functions is a hallmark of genetic and sporadic human diseases, making GTPase family members attractive though understudied targets. Specifically, the Ras superfamily of GTPases includes Arf,…