GS-493 is a Selective Protein Tyrosine Phosphatase SHP2 (PTPN11) Inhibitor
The protein tyrosine phosphatase SHP2 (also called SH-PTP2, Syp, PTP1D, and PT-P2C) is a ubiquitously expressed 68 kDa non-receptor PTP. In the inactive state, the SH2 domains of SHP2 auto-inhibit the…