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Network of Cancer Research

Reliable, unbiased and up to date information in cancer research

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Reliable, unbiased and up to date information in cancer research

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Glioblastoma Multiforme Gliocytoma

GW2974 is an EGFR/HER2 Inhibitor for Glioblastoma Multiforme Research

Louis Gilman September 21, 2023

The human EGF receptor (HER) 2 receptor tyrosine kinase is a survival factor for human cardiomyocytes. It plays an essential role in cardiac development during embryogenesis. Here, we will introduce…

Acute Myeloid Leukemia

Wu-5 is a USP10 Inhibitor for Acute Myeloid Leukemia Research

Louis Gilman September 19, 2023

Fms-related tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase expresses on hematopoietic cells. However, FLT3 plays a critical role in both normal and malignant hematopoiesis. According to existing research…

Cancer Neuropathy

Lactacystin is a Proteasome Inhibitor for Cancer and Kinds of Diseases Research

Louis Gilman September 18, 2023

Proteasomes are very large protein complexes inside all eukaryotes and archaea, and in some bacteria. In eukaryotes, they are located in the nucleus and the cytoplasm. The main function of…

Cancer

Onvansertib is an Orally Available PLK1 Inhibitor for Malignancies Research

Louis Gilman August 28, 2023

Onvansertib, a PLK1-specific ATP competitive inhibitor, blocks the phosphorylation of PLK1 substrates. Polo was first identified in Drosophila melanogaster. The family of polo-like serine/threonine kinases includes 5 members: PLK1, PLK2,…

Cancer Head and Neck Cancer

Xevinapant is an Orally Bioavailable IAPs Antagonist for Cancer Research

Louis Gilman August 2, 2023

Apoptosis is a cellular process critical to the normal development and homeostasis of multicellular organisms. Therefore, dysfunction of the apoptosis machinery has been linked to many human diseases. These diseases…

Cancer

Romidepsin (FK 228) is an HDAC Inhibitor for Cancer Research

Louis Gilman July 12, 2023

HDAC (Histone deacetylases) are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on a histone, allowing the histones to wrap the DNA more…

Cancer

CPUY201112 is a Potent Hsp90 Inhibitor for Cancer Research

Louis Gilman July 11, 2023

Hsp90 (heat shock protein 90) is a chaperone protein that helps other proteins fold correctly, stabilizes proteins against heat stress, and aids in protein degradation. Besides, it stabilizes many proteins…

Cancer Chronic Lymphocytic Leukemia

MU380 is a CHK1 Inhibitor for the Research of Chronic Lymphocytic Leukemia

Louis Gilman July 4, 2023

Checkpoint kinase 1 (Chk1) is a conserved protein kinase that is critical to the Cell cycle checkpoint during DNA damage response (DDR). Specifically, CHK1 is the regulatory factor for G2/M…

Cancer Gastric Cancer

MY-943 is a potent Tubulin Polymerization/LSD1 inhibitor that can be used for Gastric Cancer Research

Louis Gilman June 21, 2023

MY-943 is a potent tubulin polymerization and LSD1 inhibitor with anticancer activity. Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of…

Cancer Leukemia

CWI1-2 is an IGF2BP2 Inhibitor with Anti-leukemic Effects

Louis Gilman June 9, 2023

IGF2BP2, also known as IMP2, is a member of the insulin-like growth factor 2 messenger RNA-binding protein (IGF2BP) family that is highly conserved in vertebrates. Besides, it was first identified…

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  • BI 7446 is a STING Agonist for Immuno-oncology Research
  • JNJ-38877605 is an Orally Active c-Met Inhibitor for Solid Tumour Research
  • OATD-02 is an Orally Active Arginase 1/2 Inhibitor for Melanoma Research
  • INCB086550 is an Orally Active PD-L1 Inhibitor for Multiple Cancers Research
  • Panobinostat is a HDAC Inhibitor for Multiple Myeloma Research

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You Missed

Breast Cancer

BI 7446 is a STING Agonist for Immuno-oncology Research

Gastric Cancer Obesity

JNJ-38877605 is an Orally Active c-Met Inhibitor for Solid Tumour Research

Multiple Myeloma Myeloma

OATD-02 is an Orally Active Arginase 1/2 Inhibitor for Melanoma Research

autoimmune disease

INCB086550 is an Orally Active PD-L1 Inhibitor for Multiple Cancers Research

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