Pivekimab sunirine (IMGN 632) is a CD123-targeting ADC for Hematological Malignancies
CD123, the alpha chain of the interleukin 3 receptor (IL-3Rα), is a molecule found on cells that helps transmit the signal for interleukin 3, a soluble cytokine important to the immune system. Besides, Interleukin 3 (IL-3) is a soluble and pleiotropic cytokine. Additionally, IL-3 regulates the function and production...
Talacotuzumab is an IgG1 CD123-Neutralizing Monoclonal Antibody
Interleukin-3 receptor (CD123) is a soluble cytokine that is important for the immune system. CD123 is the receptor of interleukin 3 α Chain is a cytokine receptor. Meanwhile, CD123 is overexpressed in a variety of hematological malignancies. Compared with non-tumor hematopoietic stem cells, CD123 expression was high in leukemia...