Flurbiprofen is a Non-selective COX Inhibitor for Colorectal Cancer Research
Flurbiprofen, COX, Colorectal Cancer, NSAIA, NSAID, antipyretic, analgesic, osteoarthritis, rheumatoid arthritis
Flurbiprofen, COX, Colorectal Cancer, NSAIA, NSAID, antipyretic, analgesic, osteoarthritis, rheumatoid arthritis
VEGF receptor (VEGFR) is the receptor for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR VEGFR 1/2/3. By alternative splicing modification, membrane-bound (mbVEGFR) or soluble (sVEGFR)…
Colorectal cancer represents 15% of all cancers in Western countries, and is the most frequently observed. Nowadays, colorectal cancer is the world's fourth most deadly cancer with almost 900,000 deaths…
The KRAS oncoprotein is a GTPase and an essential mediator of intracellular signaling pathways. KRAS oncoprotein regulates tumor cell growth and survival. However, KRAS also is the most frequently mutated…
Kirsten rat sarcoma (KRAS) is a member of the RAS family. KRAS is a key regulator of signaling pathways responsible for cell proliferation, differentiation, and survival. KRAS mutations are genetic…
LDN-211904 is a potent and selective EphB3 inhibitor with an IC50 of 0.079 µM. Besides, LDN-211904 oxalate shows good metabolic stability in mouse liver microsomes. What’s more, LDN-211904 oxalate with cetuximab…