Topoisomerase II - Network of Cancer Research

BNS-22 is a DNA Topoisomerase II Catalytic Inhibitor

Louis Gilman August 18, 2022

Topoisomerases (DNA topoisomerases) are enzymes that catalyze changes in the topological state of DNA, regulating the overwinding or underwinding of DNA. Topoisomerases play essential roles in DNA replication, transcription, chromosome…

Bladder Cancer Cancer

Pirarubicin, an Anthracycline Antibiotics, Acts as a Topoisomerase II Inhibitor

Louis Gilman April 16, 2022

Pirarubicin has widely application in intravesical chemotherapy for bladder cancer, but drug resistance limits its efficacy; the mechanism still needs further exploration. Bladder cancer is the most common malignancy…

BNS-22 is a DNA Topoisomerase II Catalytic Inhibitor

Pirarubicin, an Anthracycline Antibiotics, Acts as a Topoisomerase II Inhibitor

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