Mitoxantrone is a Topoisomerase II Inhibitor for Leukemia Research
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia, which defined as a minimum of 5 × 109/L monoclonal B cells in the blood. However, CLL affects approximately…
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia, which defined as a minimum of 5 × 109/L monoclonal B cells in the blood. However, CLL affects approximately…
Topoisomerases (DNA topoisomerases) are enzymes that catalyze changes in the topological state of DNA, regulating the overwinding or underwinding of DNA. Topoisomerases play essential roles in DNA replication, transcription, chromosome…
Pirarubicin has widely application in intravesical chemotherapy for bladder cancer, but drug resistance limits its efficacy; the mechanism still needs further exploration. Bladder cancer is the most common malignancy…